French drugmaker Sanofi is starting a hunt for medicines to treat hearing loss, after signing a two-year research deal with privately held Dutch biotech firm Audion Therapeutics.

There are currently no disease-modifying prescription drugs for hearing loss, which affects nearly a third of people aged 65 to 74 and half of those over 75.

Audion hopes to develop small molecule drugs that can be given as a pill to improve hearing. Its first drug discovery programme is focused on regenerating lost inner ear hair cells, the main cause of most hearing loss.

The work is still at a very early stage but Audion has identified several compounds that can regenerate hair cells in laboratory tests.

Under the terms of the agreement, Sanofi has an option to licence technology rights from Audion. Financial terms were not disclosed.

Audion has technologies and molecules that originate from the work of one of its founders, Albert Edge, at the Massachusetts Eye and Ear Infirmary.

Reuters