Across:
1 One’s favourite Playmate (BEST OF FRIENDS) from Blood Brothers perhaps (BEST OF FRIENDS),
10 In a disruptive manner, involve (EMBROIL) doctor (-MB-) in Loire (Loire = E-ROIL) novel (= anagram indicator) (EMBROIL),
11 George (G-), with difficulty, steps out (-LIMPS-) with sweetheart (‘sweet’ heart = -E) (GLIMPSE) for brief look (GLIMPSE),
12 Check out (TEST) a portion of the minute steak (a portion of the ‘minute steak’ = TEST),
13 What one of those putting you in the picture would do (in FOCUS) for emphasis (FOCUS),
15 Second to none (BEST) on all sides today (BEST on all sides of grid today),
17 Withdraw a regiment immersed (‘withdraw a regiment’ immersed = WAR) in a series of battles (WAR),
19 Oh (“oh” = “O” = OXYGEN), sounds like (= homophone indicator) it’s in the tent (OXYGEN tent),
21 Director (D-) and celebrity (face = -ECAF-) knockback (= reversal indicator) French (-F) (DECAFF) coffee (DECAFF),
22 Draw (PUMP-) family (-KIN) (PUMPKIN) coming out of the plot at Halloween (PUMPKIN),
23 Globe (Globe = GOBLE-) cast (= anagram indicator) primarily from The (primarily from “the” = -T) (GOBLET) Glass ...? (glass = GOBLET),
25 Bury (ENTOMB) awful (= anagram indicator) note (note = ENTO-) from doctor (Medicinae Baccalaureus/Bachelor of Medicine = -MB) (ENTOMB),
27 Proposed to drop prose (‘proposed’ to drop ‘prose’ = pod = POD) in time capsule perhaps (POD),
29 Cover by unpatriotic (cover of “unpatriotic” = TRIO) group of musicians (TRIO),
30 Broadcast (RELAY) with electrical device (RELAY),
31 Fragment of Benjamin Disraeli’s (fragment of ‘Benjamin Disraelis’ = MIND) powers of comprehension (MIND),
34 Radical (EXTREME) needs to be embraced in next remembrance (EXTREME embraced in ‘next remembrance’),
35 Dishy Mexican type (BURRITO) set up (= reversal indicator) Polish (polish = rub = BUR-) resistance (-R-) to leaders in totalitarian organisation (leaders “in totalitarian organisation” = -ITO) (BURRITO),
36 Belts (belts = BEST L-) out (= anagram indicator) first-class (AI-) ditty from the start (‘ditty’ from the start = -D) and orchestrates (PLANS) (BEST LAID PLANS) with meticulous preparations (BEST LAID PLANS).
Down:
2 Takes a diplomatic approach (EMBASSY) rewriting (= anagram indicator) essay (essay = E-ASSY) about computer storage (megabyte = -MB-) (EMBASSY),
3 Haul (loot = TOOL) up over (= reversal indicator) device (TOOL),
4 Guy (FELLOW) with well-informed minder is missing (‘well-informed’ minder is missing/without ‘minder’ = wellfo = FELLOW),
5 Inflexibility (RIGOUR) in South America (RI-O-) over golf (-G-) in old city (-UR) (RIGOUR),
6 Sinister (EVIL) part of vaudeville (part of ‘vaudeville’ = EVIL),
7 When it’s quiet (quiet/softly = piano = -P-) in the institute (Dublin Institute of Technology = DI-T = DI-T-), time (-ERA) (DIPTERA) flies (DIPTERA),
8 Greatest footballer (George BEST) out of his mind? (FORGOTTEN) (BEST FORGOTTEN) That’s not a trip worth taking down memory lane! (BEST FORGOTTEN),
9 Describes salvage operation (BEST OF A BAD JOB) in top (BEST) office (O-) to figurehead (‘figure head’ = -F) – a (A) similar one to 6 down (“evil” similar one to BAD) on assignment (JOB) (BEST OF A BAD JOB),
14 Rap (rap = -AR P-) medley (= anagram indicator) in cool (C- -OOL) (CAR POOL) set-up for Men at Work that’s environmentally friendly (CAR POOL),
16 Square (T- square) with English (-E-) nobleman (peer) almost (r) (‘peer’ without ‘r’ = -PEE) (TEPEE) put out by the crow’s living on the plains (TEPEE put out by The Crows/ Native Americans),
18 Put down (penned) unfinished (d) (‘penned’ without ‘d’ = PENNE) pasta (PENNE),
20 Resigns from insurgents (‘resigns’ from ‘insurgents’ = nut = NUT) in Brazil (NUT),
21 Dissolve (DIE) sample of ingredients (sample of ‘ingredients’ = DIE),
24 See red (see red/flare up = BRISTLE) blister (blister = BRISTLE) blowing up (= anagram indicator),
26 There’s a theory (OPINION) there’ll be tears over this (onion = O-NION) involving detective (-PI-) (OPINION),
27 Gym work (PE-) for prop (-SET-) taking advantage (-A) (PESETA) of old European capital (capital/money = PESETA),
28 Something for someone who won’t be patient at night (hospital DAY BED) in the guest quarters (DAY BED),
32 Describe a transgression buried in (‘describe a transgression’ buried in = BEAT) Pulse (BEAT),
33 Told to get off toll road (‘told’ to get off ‘toll road’ = lroa = ORAL) for test, in a manner of speaking (ORAL).