Ireland seamer Dave Langford-Smith took three wickets and claimed two run outs but saw his side slip to an 84-run defeat to Bangladesh in their second one-day international.
Bangladesh had been restricted to 246 in Mirpur thanks to Shahriar Nafees (60) and Aftab Ahmed (61) while Langford-Smith finished with three for 43.
A number of Ireland batsman got starts in their response but Farhad Reza's five for 42 saw the Irish dismissed for 162 with 11 overs remaining.
Bangladesh had reached their total at the Shere Bangla National Stadium largely thanks to a first-wicket stand of 94 by Tamim Iqbal and Nafees. The opening pair made a patient start to the innings before 19-year-old left-hander Tamim was caught by Kevin O'Brien of the bowling of spinner Kyle McCallan for 46.
Aftab increased the run-rate in a 64-run second-wicket partnership with Nafees before the latter was run out by Langford-Smith for 60. Skipper Mohammad Ashraful (38) and a brisk 61 in 57 balls from Aftab helped Bangladesh close in on 200 before Aftab fell to Ireland captain Trent Johnston.
Langford-Smith took the wickets of Shakib Al Hasan (one), Shakib Al Hasan (two) and Mashrafe Mortaza (26) and the seamer also claimed the wicket of Raqibul Hasan with his second run-out.
Ireland's response got off to a positive start with William Porterfield and Reinhardt Strydom sharing an opening stand of 41.
Abdur Razzak, who finished with three for 27, removed Strydom (15) before all-rounder Reza captured Porterfield (25) and number three Eoin Morgan (four) in quick succession to leave Ireland in trouble at 47 for three.
Brothers Niall O'Brien (18) and Kevin O'Brien (21) were unable to build on promising starts and fell victim to Hasan (two for 16).
Ireland's hopes were ended after Andre Botha (34) and Alex Cusack (24) fell victim to Reza who mopped up the tail with Razzak to give Bangladesh a unassailable 2-0 lead in the three-match series.