Absorbable stent requires further trials, says 'Lancet'

US: THE BEST helpers are the ones that leave when their work is done

US:THE BEST helpers are the ones that leave when their work is done. That's the approach pharmaceutical giant Abbott is testing with a new type of stent - the medical device inserted into arteries to improve bloodflow.

Their absorbable stent, designed to "disappear" over time, has shown promise in two-year follow-up trials, as reported in the Lancet.

Stents have revolutionised treatment of narrowed arteries, which increase the risk of heart attack. By inserting a catheter into an artery in the leg or arm and guiding it to the narrowed stretch, doctors can widen the blood vessel and leave a supporting stent in place.

Stenting is far less invasive for the patient than a heart bypass, which involves a general anaesthetic and opening the chest, and an estimated 8,000 stenting procedures are to be carried out in Ireland this year.

READ MORE

Leaving such foreign bodies in arteries can elicit a negative reaction, and recent advances have seen coated stents that elute their own drugs on site to help overcome potentially damaging responses, such as inflammation and re-narrowing of the artery.

Abbott Vascular in Illinois is taking a step further with its absorbable stent, made from poly-L lactic acid and coated with poly-D,L-lactide.

The multi-centre Absorb study followed 29 of 30 patients with the biodegradable stents over two years and found the device was bioabsorbed and "clinically safe". One patient had a major adverse event.

The results have promise, but a Lancet commentary calls for larger trials before considering this a breakthrough.

Claire O'Connell

Claire O'Connell

Claire O'Connell is a contributor to The Irish Times who writes about health, science and innovation