Arsenal thrashed struggling Leicester 4-0 in a bad-tempered match at Highbury this afternoon. The result puts Leicester manager Peter Taylor's job in further peril.
Swedish international Fredrik Ljungberg put Arsenal 1-0 up and French international Sylvain Wiltord scored a second in the 28th minute.
Thierry Henry, added the third goal with a deflected shot after Leicester's Dennis Wise and Patrick Vieira of Arsenal were sent off following a second-half clash.
Nwanko Kanu slotted home the fourth in the final minute.
Taylor was already under pressure after Leicester were beaten 5-0 by Bolton on the opening day of the season.
With Manchester United and Liverpool playing on Sunday and Monday respectively, Everton found themselves in the unaccustomed position at the top of the Premiership after beating Middlesbrough 2-0 at Goodison Park, giving them seven points out of nine this season.
Kevin Campbell scored first with a header and Scott Gemmill rifled home the second in the second half to increase the worries for new 'Boro manager Steve McClaren.
Chelsea's Jimmy Floyd Hasselbaink scored the first Premiership goal at Southampton's new 32,000-capacity St Mary's Stadium and Mario Stanic scored a second to underline the Londoners' title aspirations in a 2-0 win.
Newly promoted Blackburn won their first match of the season, beating Tottenham 2-1 through a seventh minute Alan Mahon goal, his first for the club, and Damien Duff secured the three points in the 71st minute.
Christian Ziege pulled a goal back for Tottenham, but Glenn Hoddle's team are still without a win this season.
Injury-depleted West Ham and Leeds played out a tense goalless draw at Upton Park, leaving Leeds second in the Premiership.
West Ham's teenage star Joe Cole put the ball in the back of the Leeds net after the break, but the effort was disallowed as Svetoslav Todorov was ruled to have fouled goalkeeper Nigel Martyn.
Charlton upset Ipswich at Portman Road as Kevin Lisbie scored in the 85th minute for a 1-0 win.
Fulham and Derby ended goalless.