A commuter plane carrying 19 passengers and two crew has crashed shortly after taking off in North Carolina, US aviation authorities have said.
All 21 on the plane have died and it is feared three more people on the ground have perished.
The plane, on a flight to nearby Greenville-Spartanburg, went down near a US Airways hangar on the airport grounds, Federal Aviation Administration spokeswoman Ms Kathleen Bergen said.
"We don't know the condition of the people on board," she said.
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The crash of Flight 5481 forced the temporary closure of the airport, Charlotte's main international airfield.