AC Milan, Inter and Lazio today booked places in the Champions League next season with wins on the penultimate day of Serie A.
At the foot of the table Piacenza were relegated after Parma came back from two goals down to win 3-2.
Juventus, who wrapped up the title last week, fielded a weakened side and fell 2-1 away to relegation-threatened Reggina.
Third-placed Milan, who will face Juventus in the final of this season's Champions League, beat Bologna 3-1 with goals from Andrea Pirlo (penalty), Clarence Seedorf and Filippo Inzaghi.
Lazio secured fourth place at least with a 3-1 win over Brescia ending Chievo's hopes of a place in Europe's premier club competition.
Chievo were held to a 0-0 draw at home to Roma but are likely to take a slot in the UEFA Cup.
Along with Juventus, second-placed Inter Milan, who beat Modena 2-0, will complete the four Serie A teams in the Champions League.
Cash-strapped Lazio will be delighted to secure their place, just reward for a season with only three defeats.
Roberto Baggio put the visitors ahead in the 20th minute with a beautifully taken shot on the turn as he latched on to a defence-splitting pass from Stephan Appiah.
Lazio drew level with a penalty converted by Sinisa Mihajlovic and Brazilian Cesar put Roberto Mancini's side ahead a minute before the break.
Argentine Claudio Lopez secured the victory with Lazio's third in the 81st minute.
After reaching the final of the Champions League with an 'away goals' win over city rivals Inter on Tuesday, Milan needed to win against Bologna to avoid the danger of missing out on next year's tournament.
Coach Carlo Ancelotti fielded a full-strength side and his nerves were eased when Pirlo put them ahead from the penalty spot after Seedorf had been brought down.
Dutch midfielder Seedorf made it 2-0 with a low shot from the edge of the area five minutes after the break and Inzaghi added the third with a neat lob.
Bologna pulled a goal back through French forward Mourad Meghni in the 68th minute and then Inzaghi had a penalty saved by Gianluca Pagliuca.
Inter had little trouble away to struggling Modena. A 28th minute own goal from Simone Pavan set them on their way and then Sierra Leone forward Mohammed Kallon doubled the advantage eight minutes later.
After the stirring 3-1 Champions League win over Real Madrid on Wednesday, Juventus coach Marcello Lippi left out several regulars including Alessandro Del Piero, Pavel Nedved and David Trezeguet for the trip south to face Reggina.
Reggina went ahead in the 18th minute with a close-range effort from David Di Michele but six minutes later an error from Reggina keeper Emanuele Belardi gifted Uruguayan Marcelo Zalayeta an equaliser for Juve.
Striker Emiliano Bonazzoli got the winner for Reggina six minutes after the restart with a near post header from a corner.
The win keeps Reggina's hopes of staying in the top flight alive although they face a tense final week after two goals from Cristiano Doni gave fellow-strugglers Atalanta a 2-1 win over already-relegated Como.
Piacenza will play in Serie B after letting a two goal lead slip against Parma. Brazilian Adriano equalised before Romanian
Adrian Mutu grabbed the winner in the 89th minute. The last relegation place will be taken by either Reggina, Atalanta or Modena.