Fifteen Afghans, most of them children, were killed by a roadside bomb in the southern Kandahar province today.
The latest attack came after the publication of a report from the United Nations which showed a record number of civilian deaths in the month of May.
Afghanistan's interior ministry said eight children, four women and three men were killed when a bomb hit their vehicle in the Haji Lahore region of southern Kandahar province, the birthplace of the Taliban and one of the most violent regions in Afghanistan.
Another six civilians were wounded when insurgents fired mortar rounds into a district in volatile eastern Kunar province, near the border with Pakistan, the ministry said.
The United Nations Assistance Mission in Afghanistan (Unama) said in its report it had documented 368 "conflict-related" civilian deaths in May this year and 593 civilian injuries.
"More civilians were killed in May than in any other month since 2007 when Unama began documenting civilian casualties," said Georgette Gagnon, the Unama director for human rights.
"We are very concerned that civilian suffering will increase even more over the summer fighting season which historically brings the highest numbers of civilian casualties. Parties to the conflict must increase their efforts to protect civilians now," she said in a statement.
Violence across Afghanistan in 2010 hit its worst levels since the Taliban were toppled by US-backed Afghan forces in late 2001. It has flared again since the Taliban began their spring offensive at the start of May. Military deaths hit record levels in 2010 - and are following the same pattern this year - but civilians continue to bear the brunt of the conflict.
Civilian casualties are one of the most contentious issue between Afghan President Hamid Karzai and his Western backers, even though figures by the United Nations show that insurgents are responsible for the overwhelming majority.
In its latest findings, the United Nations said "anti-government elements" were responsible for 301 of the civilian deaths in May, or 82 per cent. Forty-five civilians, or 12 per cent, were killed by "pro-government forces" in May, it said.
The remaining 22, or 6 per cent, could not be attributed to either side and were most likely the result of Afghan civilians being caught in the crossfire.
The figures roughly track previous statistics released by the United Nations.
UN figures showed that 2,777 Afghan civilians were killed in 2010, a 15 per cent rise on 2009. That report said insurgents were responsible for three-quarters of those killed.
Nato-led forces have significantly tightened the use of "night raids" and air strikes as they hunt insurgents. The 2010 UN report found there was a 52 percent drop in civilian deaths from air strikes compared with 2009.