Liverpool manager Rafael Benitez gives French striker Djibril Cisse a start in tonight's Champions League group G qualifier away to Anderlecht.
The £14 million signing starts up front on his own, with Luis Garcia in a roving role and Mohamed Sissoko also given licence to attack against an Anderlecht side who have created a competition record by losing nine successive group matches.
Peter Crouch and Fernando Morientes are on the bench, as is Harry Kewell who is primed for a comeback since injury in the Champions League final in Istanbul.
Chelsea, meanwhile, rest goalkeeper Petr Cech as Carlo Cudicini starts between the posts for the visit of Real Betis to Stamford Bridge.
Republic of Ireland international Damien Duff misses out because of his knee injury but the rest of the Chelsea team is along expected lines.
Anderlecht:Proto, Deschacht, Tihinen, Deman, Vanden Borre, Goor, Vanderhaeghe, Wilhelmsson, Zetterberg, Mpenza, Jestrovic. Subs: Zitka, Zewlakow, Baseggio, Pujol, Hasi, Akin, Traore.
Liverpool:Reina, Josemi, Carragher, Hyypia, Traore, Sissoko, Alonso, Hamann, Riise, Luis Garcia, Cisse. Subs: Carson, Finnan, Kewell, Crouch, Morientes, Warnock, Zenden.
Chelsea:Cudicini, Ricardo Carvalho, Terry, Gallas, Del Horno, Makelele, Wright-Phillips, Lampard, Essien, Joe Cole, Drogba. Subs: Cech, Crespo, Geremi, Diarra, Paulo Ferreira, Gudjohnsen, Huth.
Real Betis:Doblas, Melli, Juanito, Rivas, Oscar Lopez, Varela, Miguel Angel, Rivera, Edu, Oliveira, Joaquin. Subs: Contreras, Dani, Arzu, Capi, Nano, Assuncao, Xisco.