Manchester City came from behind to claim a 1-1 draw in their derby with United at Old Trafford.
City, who have not won at the home of their rivals since 1974, played well in the first half but were caught out by Ruud van Nistelrooy just before the interval.
But the visitors hit back to maintain their unbeaten record when Joey Barton deflected a Darius Vassell shot in for an equaliser after 76 minutes.
Michael Owen endured a frustrating Newcastle debut as Fulham claimed a 1-1 draw from their Barclays Premiership trip to St James' Park.
England striker Owen started alongside Alan Shearer and Albert Luque in attack but Newcastle, who had Scott Parker sent off, still have problems in defence.
The visitors took advantage of their defensive uncertainty to claim the opening goal in the 13th minute.
Fulham were gifted possession and Jean-Alain Boumsong slipped trying to cut out a Luis Boa Morte pass allowing American Brian McBride to strike.
Steve Carr rattled the bar in the second half as the Magpies fought back and an equaliser finally came from Charles N'Zogbia on 78 minutes.
But Newcastle were left hanging on after Parker was dismissed for a second booking.
Champions Chelsea moved up a gear after a goalless first half to beat bottom side Sunderland 2-0 at Stamford Bridge.
Geremi put Jose Mourinho's side ahead in the 54th minute at Stamford Bridge when he capitalised on a mistake by Andy Welsh.
Didier Drogba added the second from a fine Damien Duff cross eight minutes from time.
Darren Bent scored his fifth goal of the season as Charlton maintained their 100 per cent record with a 1-0 win at Birmingham. Bent headed home from a Jerome Thomas cross after 15 minutes.
Jimmy Bullard struck in the last minute as Wigan came from behind to snatch a 2-1 win at West Brom.
Jonathan Greening had put the Baggies ahead when he rifled home in the 26th minute after goalkeeper Mike Pollitt punched.
But David Connolly responded five minutes before the break and Bullard had the final say.
Portsmouth claimed their first win of the season courtesy of a Duncan Ferguson own goal at Goodison Park.
Everton striker Ferguson put through his own net on the hour mark to hand Pompey a 1-0 success.
Tottenham and Liverpool had to settle for a goalless draw after an entertaining encounter at White Hart Lane.
Both sides had second-half goals disallowed after corners were ruled to have swung out of play.
Spurs debutant Grzegorz Rasiak was the first to be denied from a Michael Carrick cross and Peter Crouch was also frustrated after a Steven Gerrard corner.