Gardaí in Dungarvan and officials from the Department of Agriculture are investigating the deaths of 42 cattle on a farm at Colligan, Co Waterford.
The discovery follows the deaths of 60 cattle found starved on a farm in Co Cork earlier this week.
Dungarvan gardaí received a call from a veterinary inspector on Wednesday regarding the discovery of carcasses at Knockenpower Lower in Colligan.
Having examined the scene with a senior veterinary inspector from the Department of Agriculture, they confirmed that 42 of the animals on the farm were dead. A further 40 live animals were examined and are being cared for on the farm by their owner, with sources suggesting they are in "reasonable" condition.
A file is to be prepared for the Director of Public Prosecutions.
Sgt Mick Leacy said it was "very unusual" for so many dead animals to be found. "A clean-up operation is continuing on the farm in Colligan with the carcasses due to be brought to Waterford for rendering."
A Department of Agriculture spokesman stressed that there was no evidence of a risk to public or animal health as a result of the two unrelated incidents in Cork and Waterford.