Wales 9 England 43
England's second team heaped humiliation on Wales as the red rose brigade launched their World Cup warm-up campaign by posting a 14th successive Test match victory.
Clive Woodward had total faith in his side of World Cup wannabes and they responded by brushing aside Wales coach Steve Hansen's strongest available line-up in record fashion despite fly-half Alex King missing six kicks at goal.
While England celebrated, Wales could only reflect on an 11th consecutive defeat and the stark realisation that World Cup quarter-final status looks beyond them, given that their qualifying group includes New Zealand, Italy and Canada.
Hansen, who has consistently pleaded for patience from long-suffering Welsh fans, could not possibly defend a display of such abject incompetence. England rested the entire starting XV that accounted for world champions Australia in Melbourne two months ago but were still in a different class.
Flanker Lewis Moody, wing Dan Luger, number eight Joe Worsley, centre Stuart Abbott and replacement hooker Dorian West scored tries, while King kicked 16 points and his replacement Dave Walder landed a late conversion.
Wales captain Stephen Jones slotted three penalties but in the end England broke their all-time record winning margin in Cardiff - a 44-15 success two years ago.
Where Hansen goes from here is anyone's guess but fans may suggest a one-way ticket back to his native New Zealand.
England made all the early running, producing some stunning ball-retention inside the opening minute to put Wales under pressure.
It mattered little that the Six Nations champions were without so many star names, yet England should still have capitalised after the early chances they manufactured.
King, making his first Test match start, rifled a 38-metre penalty chance narrowly wide, before flanker Martin Corry's pass to wing James Simpson-Daniel split open a naive Welsh defence.
Simpson-Daniel found back-row men Moody and Worsley in support, but a promising move fizzled out and Wales gained their first scoring opportunity on 12 minutes that Jones accepted through a comfortable penalty strike.
King tied the scores four minutes later before a second penalty ensured that England ended an industrious opening quarter 6-3 ahead.
And it got better for England when a robust charge by Shaw set up an imposing attacking platform from which England's forwards predictably made hay.
Wales, having defended admirably for a lengthy period, just could not cope with English momentum, and Moody - on his first competitive outing for six months - powered over for a try that King converted. King's angled conversion opened up a 10-point advantage.
Jones brought Wales back to within a converted try through his second penalty 13 minutes before the break.
England though, continued to play all the rugby, and King's short-range drop-goal restored the 10-point gap.
England lost injured hooker Mark Regan as half-time approached - experienced Leicester forward West replaced him - and the final act of a lively half was orchestrated by the Welsh backs.
With the England defence back-pedalling, prop Gethin Jenkins went agonisingly close to a score, yet Wales had to content themselves with another Jones penalty and a 16-9 interval deficit.
King missed an easy penalty within five minutes of the restart, drifting his kick inexplicably wide but England comfortably maintained territorial control.
King's fourth penalty miss from six attempts allowed Wales a further reprieve. His tribulations on a perfect day for kicking only served to emphasise what a goalkicking genius England possess in Jonny Wilkinson.
It went from bad to worse from King, who botched a third kick in what was potentially a damaging 11-minute spell as far as his World Cup prospects were concerned, and Wales somehow continued clinging on.
There was no respite during the closing 25 minutes though, as Luger, Worsley, Abbott and West confirmed an embarrassing gulf in class.