Tyrone boss Mickey Harte welcomes back fit-again Kevin Hughes at midfield for the Division 1A clash with Galway on Sunday.
Hughes missed last week's defeat to Roscommon with an ankle injury.
Fellow midfielder Cormac McAnallen has yet to shake off the kneecap injury that kept him out of last week's game and Harte rates the Eglish star as extremely doubtful.
A vacancy, however, has been left in midfield in the hope that McAnallen passes a late fitness test.
Colin Holmes, who deputised in midfield last time out, switches to full back to replace Chris Lawn who has a groin strain.
Stephen O'Neill, scorer of two points against Roscommon, is troubled with a hamstring injury and misses out.
Ryan McMenamin drops to the right corner from half-back in a direct swap with Conor Gormley while, up front, Owen Mulligan switches to full forward with Sean Kavanagh moving into the corner.
Tyrone (SF v Galway):P McConnell, R McMenamin, C Holmes, M McGee, C Gormley, G Devlin, P Jordan, AN Other, K Hughes, R Mellon, B McGuigan, B Dooher, F McGuigan, O Mulligan, S Cavanagh.