Brian Ashton is determined to see "the real England" take centre stage in Sunday's Six Nations clash against Italy.

England were floored by what the head coach termed "six minutes of madness" when they blew a 13-point lead and saw Wales register their first Twickenham victory for 20 years.

But Ashton also insists that second-half implosion is out of the system as a much-changed England team prepares for Rome.

While outhalf Jonny Wilkinson has avoided the axe despite producing arguably his poorest England performance during a 66-cap Test career, he is among only 10 players who remain from last Saturday's starting line-up.

The injured Mike Tindall (bruised liver), David Strettle (foot), Lewis Moody (Achilles) and Tom Rees (knee ligament) had already disappeared off the radar. They have now been joined by giant prop Andrew Sheridan, who misses the Stadio Flaminio showdown after being admitted to hospital.

While Tindall remains under observation at London's Hammersmith Hospital, Sheridan is being treated for an abscess adjacent to an Achilles tendon.

He received intravenous antibiotics and underwent a minor operation to drain the infection, but he has not recovered sufficiently to confront the revered Italian tighthead Martin Castrogiovanni.

Wasps prop Tim Payne takes over from Sheridan, with Newcastle centre Jamie Noon replacing Tindall in an all-Falcons midfield alongside Wilkinson and Toby Flood.

It will be Noon's first England appearance since a knee injury forced him out of the World Cup last September.

Rugby league recruit Lesley Vainikolo, who went on for Strettle last Saturday, retains his place to gain a first Test start, while backrow switches see Bath flanker Michael Lipman and Harlequins number eight Nick Easter included.

Lipman, London-born but educated in Australia, wins a fourth cap - he has not yet played in the Six Nations - with World Cup regular Easter returning following a knee injury that has sidelined him since December 29th.

Easter's availability means no place in the starting line-up for Gloucester's Luke Narraway, who started against Wales but now drops down to bench duty.

England, having lost 15 of their last 16 away matches, cannot afford a mental switch-off on Sunday, even though they average 46 points from four previous Six Nations visits to Rome.

Ashton said: "There is a real determination to make sure when we get out on the field on Sunday, for the whole of the game, to see the real England.

"It wasn't the brightest rugby (against Wales). It all happened in six minutes really, from minute 61 to minute 67. Seventeen points were scored, and I don't think the opposition had to do too much to contribute to them.

"Now it has happened, you can put measures in place to prevent it happening again. You would hope the players have learnt their lessons.

"There is a strong argument to say they should have learnt that already, but it is very rare to see in international rugby a team so clearly on top give away 17 points in that fashion."

Ashton summed up the determined mood: "There is just massive disappointment from last weekend. There are one or two angry men in the squad, quite rightly. They ought to be."

Teams for Rome on Sunday