Today

Aston Villa (10) v Wimbledon (15)

Villa will be without £7 million striker Stan Collymore, who starts a three-match ban. But Villa hope Republic of Ireland international defender Steve Staunton will be fit to return after shaking off a knee injury.

Wimbledon are struggling in attack as promising striker Jason Euell has been ruled out for five weeks after dislocating a shoulder and Jon Goodman is facing an operation for cruciate knee ligament damage.

Last season: Villa 5-0 Wimbledon, Wimbledon 0-2 Villa

Last five league matches: Aston Villa W W L D W, Wimbledon W L W D L

Top scorers: Dwight Yorke (Aston Villa) 3; Jason Euell, Carl Cort (Wimbledon) 4

Match odds: H 8/13 A 4/1 D 12/5

Referee: K Burge (Tonypandy)

Blackburn (3) v Southampton (19)

Stuart Ripley has recovered well from a hamstring injury and could return for Blackburn after coming through 60 minutes of a reserves match on Thursday. Jason Wilcox is suspended and defenders Chris Coleman and Marlon Broomes are sidelined through injury, but striker Chris Sutton should be fit.

Southampton midfielder Matt Le Tissier misses the trip after damaging a thigh muscle in midweek but new signing David Hirst is in line to start with striker Egil Ostenstad out and Mike Evans struggling.

Last season: Blackburn 2-1 Southampton, Southampton 2-0 Blackburn.

Last five league matches: Blackburn L D D D W, Southampton L D L L W

Top scorers: Chris Sutton (Blackburn) 10; Kevin Davies (Southampton) 6

Match odds: H 8/15 A 5/1 D 12/5

Referee: G Willard (Worthing)

Chelsea (5) v Leicester (4)

Chelsea's French winger Bernard Lambourde is available because his suspension does not begin until tomorrow. Dennis Wise is suspended and Gustavo Poyet is out for the season but Celestine Babayaro may make his debut and Eddie Newton and David Lee could play their first league games this season.

Leicester should be boosted by the return of midfielder Muzzy Izzet and defender Pontus Kamark, and Emile Heskey may figure after recovering from a groin strain. But Garry Parker (thigh), Steve Walsh and Ian Marshall (groin) are still sidelined.

Last season: Chelsea 2-1 Leicester, Leicester 1-3 Chelsea

Last five league matches: Chelsea W L D W L, Leicester W W D W L

Top scorers: Gianluca Vialli (Chelsea) 5; Ian Marshall (Leicester) 4

Match odds: H 4/7 A 9/2 D 12/5

Referee: U Rennie (Sheffield)

Crystal Palace (13) v Arsenal (1)

Emmanuel Petit makes a welcome return to the side after recovering from an ankle injury picked up on international duty. Dutch winger Marc Overmars is out with an ankle problem and Portuguese ace Luis Boa Morte is set for his first Premiership start, while fullback Lee Dixon is struggling with a groin injury.

Steve Coppell is set to hand new signing Ivano Bonetti his Crystal Palace debut and former Wolves star Neil Emblen could return to the defence.

Last season: No corresponding fixtures

Last five league matches: Crystal Palace L W D D L, Arsenal W W W D W

Top scorers: Attilio Lombardo (Crystal Palace) 3; Dennis Bergkamp (Arsenal) 11

Match odds: H 3/1 A 4/5 D 9/4

Referee: S Dunn (Bristol)

Derby (6) v Manchester Utd (2)

Alex Ferguson is set to make 10 changes from the side that went out of the Coca-Cola Cup to Ipswich. Peter Schmeichel, Gary Neville, Henning Berg, Gary Pallister, Denis Irwin, David Beckham, Nicky Butt, Ryan Giggs, Teddy Sheringham and Ole Gunnar Solskjaer are all likely to return. David May is also back in contention.

Francesco Baiano is set to return for Derby, with Igor Stimac and Stefano Eranio likely to miss out. Defender Jacob Laursen could make a shock return.

Last Season: Derby 1-1 Man Utd, Man Utd 2-3 Derby

Last five league matches: Derby W L W W W, Man Utd W D D L W

Top scorers: Francesco Baiano, Paulo Wanchope (Derby) 6; Teddy Sheringham, Paul Scholes (Man Utd) 3

Match odds: H 9/4 A 11/10 D 2/1

Referee: G Poll (Tring)

Everton (18) v Liverpool (7)

Everton will be without the suspended Slaven Bilic, while Howard Kendall has added Terry Phelan, Gavin McCann and Neville Southall to the 13 who figured in the midweek Coca-Cola Cup defeat against Coventry. Danny Cadamarteri is certain to start up front.

Neil Ruddock looks certain to play his first Premiership game, replacing the injured Phil Babb (cracked ribs). Rob Jones and Jason McAteer have recovered from minor injuries but Jamie Redknapp (calf) is unlikely to make the squad.

Last season: Everton 1-1 Liverpool, Liverpool 1-1 Everton

Last five league matches: Everton L W L D L, Liverpool W D W L W

Top scorers: Danny Cadamarteri (Everton) 4; Robbie Fowler, Patrick Berger (Liverpool) 4

Match odds: H 15/8 A 6/5 D 9/4

Referee: M Reed (Birmingham)

Leeds (9) v Newcastle (8)

Leeds striker Jimmy Hasselbaink serves the second game of a three-match ban but skipper David Hopkin is expected to recover from a calf injury.

Italian under-21 defender Alessandro Pistone and former England captain Stuart Pearce are unlikely to figure for Newcastle, but Rob Lee (thigh) and Keith Gillespie (groin) have recovered and should play.

Last season: Leeds 0-1 Newcastle, Newcastle 3-0 Leeds

Last five league matches: Leeds W L W W D, Newcastle L W W L W

Top scorers: Rod Wallace (Leeds) 7; Faustino Asprilla (Newcastle) 6

Match odds: H 6/4 A 6/4 D 11/5

Referee: D Elleray (Harrow-on-the-Hill)

West Ham (11) v Bolton (17)

West Ham's Tim Breacker, who damaged a hamstring in Wednesday's Coca-Cola Cup defeat of Aston Villa, is out for three weeks, but Iain Dowie, who went off at half-time with ankle trouble, has been passed fit to play. John Moncur and Andy Impey should be fit, but Ludek Miklosko (knee) has been ordered to rest.

Dean Holdsworth will partner Peter Beardsley up front for Bolton at the expense of John McGinlay and Robbie Elliott, Neil Cox and South African international Mark Fish are still sidelined. Andy Todd and Nathan Blake are both suspended.

Last season: No corresponding fixtures

Last five league matches: West Ham L L L W L, Bolton L D D D L

Top scorers: John Hartson (West Ham) 10; Nathan Blake (Bolton) 5

Match odds: H 4/5 A 3/1 D 9/4

Referee: G Ashby (Worcester)

Tomorrow

Tottenham (14) v Sheff Wed (16)

Tottenham centre-half Ramon Vega is fighting to shake off a slight ankle injury and inspirational captain Gary Mabbutt is also under treatment for a thigh strain which could rule him out.

Wednesday's new midfielder Petter Rudi is set to make his debut and defender Jon Newsome returns from a three week lay-off with a hamstring injury. Peter Atherton, Andy Booth and Graham Hyde are injured, while Patrick Blondeau is suspended.

Last season: Tottenham 1-1 Sheff Wed, Sheff Wed 2-1 Tottenham

Last five league matches: Tottenham L D D D L, Sheff Wed L D L D W

Top scorers: Les Ferdinand (Tottenham) 3; Benito Carbone (Sheff Wed) 7

Match odds: H 4/5 A 3/1 D 9/4

Referee: J Winter (Stockton-on-Tees)