Saturday

Arsenal (2) v Chelsea (5)

Thierry Henry is set to return for Arsenal after missing the past two games with a hamstring injury. Martin Keown is doubtful because of a back problem and Fredrik Ljungberg (fractured rib) and Davor Suker (groin) are definitely ruled out. Arsene Wenger must decide whether to restore Emmanuel Petit - who was rested until the second half against West ham - to the starting line-up.

Chelsea are without defenders Albert Ferrer, Celestine Babayaro and Jes Hogh. Right-back Ferrer has an ankle problem, so Mario Melchiot will continue to deputise. Hogh has a similar injury. Left-back Babayaro has not recovered from an Achilles injury - so Jon Harley is set to start.

Last season: Arsenal 1 Chelsea 0, Chelsea 0 Arsenal 0

Last five league matches: Arsenal W W W W W, Chelsea W L D L W

Top scorers: Thierry Henry 24 (Arsenal): Tore Andre Flo 19 (Chelsea)

Match odds: H 4-5 A 11-4 D 9-4

Referee: M Reed (Birmingham)

Coventry (14) v Sheff Wed (19)

Coventry boss Gordon Strachan will leave selection to the last moment. Colin Hendry is out with a broken nose and fractured eye socket and Coventry are also without Stephen Froggatt (ankle), Cedric Roussel (knee), Carlton Palmer (ankle and knee), David Burrows (knee) and Marcus Hall (knee). Noel Whelan is doubtful with a calf injury.

Sheffield Wednesday caretaker-manager Peter Shreeves is likely to name the same team which lost 3-0 to Leeds on Sunday as his side look to avoid the defeat which could consign them to the first division.

Last season: Sheff Wed 1 Coventry 2, Coventry 1 Sheff Wed 0

Last five league matches: Coventry L L W L L, Sheff Wed L W W L L

Top scorers: Robbie Keane 18 (Coventry), Niclas Alexandersson, Gilles De Bilde 9 (Sheff Wed)

Match odds: H 11-10 A 7-4 D 5-2

Referee: S Bennett (Orpington)

Derby (16) v Newcastle (12)

Derby could be without three key players as they aim to secure their Premiership status. Right wing back Rory Delap is suspended while midfielder Seth Johnson also serves a one-match ban. Branko Strupar is doubtful but Lars Bohinen is now available and Tony Dorigo is back in the squad after illness.

Newcastle welcome Kevin Gallacher back from a thigh injury and Didier Domi is also fit again but goalkeeper Steve Harper is left out as he prepares to undergo surgery on a knee injury early next week. Steve Howey misses out following a hamstring strain.

Last season: Derby 3 Newcastle 4, Newcastle 2 Derby 1

Last five league matches: Derby D L D W D, Newcastle L L D W D

Top scorers: Branko Strupar 16 (Derby); Alan Shearer 33 (Newcastle)

Match odds: H 7-5 A 6-4 D 9-4

Referee: A Wiley (Burntwood)

Leicester (9) v Bradford (17)

Leicester manager Martin O'Neill hopes to field the same side that beat Liverpool at Anfield on Wednesday night. Tim Flowers looks likely to be out with a back injury and Pegguy Arphexad stands by. Bradford manager Paul Jewell looks set to name an unchanged side for the third successive game as they chase Premiership survival.

Last season: No corresponding fixture

Last five league matches: Leicester W L D W W, Bradford L L D W W

Top scorers: Tony Cottee 12 (Leicester); Dean Windass 10 (Bradford)

Match odds: H 5-4 A 8-5 D 12-5

Referee: S Dunn (Bristol)

Manchester Utd (1) v Tottenham (10)

United will be back to full strength for their last home game of the season. David Beckham should return along with Paul Scholes and Andy Cole. Roy Keane and Gary Neville are also set to return after injuries. Steffen Freund returns to the Spurs squad after suspension but defender Luke Young is ruled out with a cracked rib.

Last season: Man Utd 2 Tottenham 1, Tottenham 2 Man Utd 2

Last five league matches: Man Utd W W W W W, Tottenham L L W W D

Top scorers: Dwight Yorke 24 (Man Utd); Steffen Iversen 18 (Tottenham)

Match odds: H 1-3 A 7-1 D 3-1

Referee: A Wilkie (Chester-Le-Street)

Middlesbrough (13) v Watford (20)

Middlesbrough will be without defender Christian Ziege (groin) and midfielder Mark Summerbell who dislocated his shoulder during the 2-2 draw with Newcastle on Tuesday night.

Watford's Richard Johnson has suffered a cruciate ligament injury and Nick Wright has been told his career is under threat from knee problems. Peter Kennedy is also missing for tomorrow's trip but Tommy Mooney returns to face his home-town club.

Last season: No corresponding fixture

Last five league matches: Middlesbrough L L D W D, Watford D L L L L

Top scorers: Hamilton Ricard 14 (Middlesbrough); Heidar Helguson 6 (Watford)

Match odds: H 4-11 A 6-1 D 3-1

Referee: P Jones (Loughborough)

Sunderland (7) v West Ham (8)

Sunderland are without Alex Rae, who completes a two-match ban, and Darren Williams (groin). Milton Nunez is wanted by Honduras for a World Cup qualifier. West Ham manager Harry Redknapp awaits late fitness tests on Rio Ferdinand (ankle) and Javier Margas (ill). Frederic Kanoute could drop out with a back problem - and Redknapp has 10 other first-team regulars on the injured list.

Last season: No corresponding fixture

Last five league matches: Sunderland W L W L D, West Ham W W W L L

Top scorers: Kevin Phillips 29 (Sunderland); Paolo Di Canio 17 (West Ham)

Match odds: H 5-6 A 11-4 D 11-5

Referee: N Barry (Scunthorpe)

Wimbledon (18) v Aston Villa (6)

New Wimbledon manager Terry Burton has no fresh injury problems. John Hartson's suspension for his red card at Bradford last weekend does not start until next weekend.

Villa are set to recall leading scorer Dion Dublin. Alan Wright, who missed the Sunderland game, will return at left-back in place of Najwan Ghrayib, but Steve Stone (knee) and Ian Taylor (hamstring) are both out again.

Last season: Wimbledon 0 Aston Villa 0, Aston Villa 2 Wimbledon 0

Last five league matches: Wimbledon L L L L L, Aston Villa W W W D D

Top scorers: Carl Cort 17 (Wimbledon); Dion Dublin 14 (Aston Villa)

Match odds: H 5-4 A 8-5 D 12-5

Referee: M Halsey (Welwyn Garden City)

Sunday

Liverpool (4) v Southampton (15)

Liverpool are likely to recall Robbie Fowler to their starting line-up with either Michael Owen or Emile Heskey making way. Steven Gerrard is likely to be sidelined again by a groin problem.

Southampton are without Stuart Ripley. Jason Dodd faces a late fitness test on an ankle injury but James Beattie is hopeful of returning after missing the Leicester game. Portuguese striker Dani Rodrigues could make another appearance after making his first team debut last weekend.

Last season: Liverpool 7 Southampton 1, Southampton 1 Liverpool 2

Last five league matches: Liverpool W W D L L, Southampton W W L L L

Top scorers: Michael Owen 13 (Liverpool); Marian Pahars 13 (Southampton)

Match odds: H 1-5 A 8-1 D 9-2

Referee: P Alcock (Halstead)

Odds supplied courtesy of William Hill