All-Ireland champions Tyrone must find a route past Louth in next Saturday's football qualifier replay at Omagh without injured duo Stephen O'Neill and Ger Cavlan.
Raymond Mulgrew replaced Cavlan early in the second half of Saturday's 2-16 to 2-16 draw in Navan after the 2003 All-Ireland winner damaged his groin taking a free from the ground. O'Neill limped to the line just after the hour mark when his recent hamstring problem returned.
Mulgrew and Enda McGinley, a half-time replacement for Peter Donnelly, did contribute two points apiece in the dramatic contest, but the current injury-list leaves Mickey Harte's team desperately short of proven scoring forwards.
Team captain Brian Dooher has been nursing a knee problem for two weeks and is unlikely to feature for 70 minutes, while Kevin Hughes' four-week suspension resulting from a red card against Derry on May 28th only ends at midnight on Saturday night. The versatile Joe McMahon is also likely to remain on the bench, alongside long-term injury victim Brian McGuigan.
Meanwhile, both Laois and Dublin must definitely plan without one key player ahead of the Leinster football semi-final at Croke Park on Sunday at 2pm (live on RTÉ).
Laois captain Gary Kavanagh damaged his knee playing for county champions Stradbally recently, while Dublin midfielder Darren Magee is to have a cast removed from his scaphoid bone this week.
Laois dual player Darren Rooney missed the 7-18 to 2-13 hurling championship annihilation at the hands of Galway on Saturday, but may yet recover in time to line out at wing back for the footballer.
Dublin fielded recovering defenders Stephen O'Shaughnessy, Paddy Christie and Collie Moran for a challenge match against Louth last week, ensuring all three are available for selection this evening.
Tickets for Croke Park are available this week from the Leinster Council offices in Portlaoise and the Cusack Stand ticket office from tomorrow until Saturday evening at 4pm. Both county boards will also be distributing tickets.
There is also good news for Tipperary hurling as Philly Maher, Benny Dunne, Séamus Butler and Paul Kelly have all been passed fit to start the Munster final against Cork in Thurles this Sunday. Babs Keating sits down with his selectors this evening.
Cork manager John Allen also has a clean bill of health ahead of RTÉ's second live game (4pm).
