Arsenal (2nd) v Man City (10th) David Seaman (shoulder) is ruled out so veteran John Lukic (40), plays his first Premiership match for three years. Tony Adams (back) returns while Martin Keown and Gilles Grimandi are back after midweek European bans. Ashley Cole will make his first home start in the Premiership. Shaun Goater and new signing Laurent Charvet will make their Premiership debuts for Manchester City.
Last season: No corresponding fixture.
Last five league matches: Arsenal W D W W W, Man City D D L W W.
Top scorers: Henry (Arsenal) 6; Wanchope (City) 6.
Match odds: H 2/7 A 7/1 D 7/2.
Referee: R Styles (Waterlooville).
Aston Villa (12th) v Charlton (7th) Villa are without suspended midfielder Lee Hendrie who is set to be replaced by George Boateng. Charlton's Richard Rufus is battling to be fit but Matt Svensson's goalscoring return from injury last weekend has boosted options in attack.
Last season: No corresponding fixture.
Last five league matches: Aston Villa W D W L D, Charlton W W D L W.
Top scorers: Joachim (Villa) 3; Johansson (Charlton) 7.
Match odds: H 8/13 A 4/1 D 9/4.
Referee: D Gallagher (Banbury)
Chelsea (11th) v Tottenham (8th) Claudio Ranieri will be tempted to stick with the side which routed Coventry 6-1 last weekend. Graeme Le Saux is suspended and Mario Stanic is recovering from knee surgery. Steffen Freund and Luke Young return for Spurs, who are without Oyvind Leonhardsen (hamstring).
Last season: Tottenham 0 Chelsea 1, Chelsea 1 Tottenham 0.
Last five league matches: Chelsea L D W L W, Tottenham L D L L W
Top scorers: Hasselbaink (Chelsea) 9; Rebrov (Tottenham) 5.
Match odds: H 8/13 A 4/1 D 9/4.
Referee: S Dunn (Avon).
Ipswich (6th) v Middlesbrough (16th) Ipswich should keep the same side that won 2-0 at Bradford. Middlesbrough's Alen Boksic has failed to shake off a knee injury, and joins Paul Ince (knee), Ugo Ehiogu (calf), Keith O'Neill, Phil Stamp (both hamstring) and Robbie Mustoe (shoulder) on the sidelines.
Last season: No corresponding fixture.
Last five league matches: Ipswich W D W D W, Middlesbrough D D W L L.
Top scorers: Stewart (Ipswich) 5; Boksic (Middlesbrough) 6
Match odds: H 11/10 A 2/1 D 11/5.
Referee: S Lodge (Barnsley).
Leicester (5th) v Derby (20th) Stefano Eranio, Simo Valakari and Giorgi Kinkladze return to Derby's squad, but they will be without striker Branko Strupar (hernia). Leicester striker Darren Eadie is struggling with a knee problem, so Ade Akinbiyi should return.
Last season: Derby 3 Leicester 0, Leicester 0 Derby 1.
Last five league matches: Leicester W D D L L, Derby L D L L L.
Top scorers: Akinbiyi, Elliott, Izzet, Taggart (Leicester) 2; Christie, Strupar (Derby) 4.
Match odds: H 4/6 A 4/1 D 21/10.
Referee: G Poll (Tring).
Man Utd (1st) v Southampton (17th) Teddy Sheringham is fit for Manchester United after recovering from his calf injury. However United could be without Ronny Johnsen (ankle). Roy Keane (hamstring) has resumed training, but may not be risked. Southampton are waiting on the fitness of midfielders Matthew Oakley (calf) and Jo Tessem (foot). Kevin Davies is likely to replace Matthew Le Tissier (knee).
Last season: Southampton 1 Man Utd 3, Man Utd 3 Southampton 3
Last five league matches: Man Utd W D L W W, Southampton W W L D L
Top scorers: Sheringham (Man Utd) 8; Pahars (Southampton) 6.
Match odds: H 1/5 A 10/1 D 4/1.
Referee: A D'Urso (Billericay).
Sunderland (13th) v Coventry (15th) Sunderland' Niall Quinn has passed a fitness test on a knee ligament problem. With Kevin Kilbane suspended, Don Hutchison is expected to return, although Peter Reid is also considering John Oster and Michael Reddy. Chris Kirkland, sent off last weekend at Chelsea, is back between the posts for Coventry.
Last season: Coventry 3 Sunderland 2, Sunderland 1 Coventry 1
Last five league matches: Sunderland W D D W D, Coventry L L D W L
Top scorers: Phillips (Sunderland) 5; Aloisi (Coventry) 5.
Match odds: H 8/13 A 4/1 D 9/4.
Referee: S Bennett (Orpington).
West Ham (18th) v Newcastle (4th) Ian Pearce will make his first start for West Ham for nearly 15 months - he has not played since damaging cruciate ligaments. Full back Didier Domi is a doubt for Newcastle after he reported in sick and with Marcelino and Warren Barton both out with groin injuries, manager Bobby Robson has drafted Steve Caldwell and Andy Griffin into the squad. Striker Carl Cort (hamstring) is doubtful.
Last season: West Ham 2 Newcastle 1, Newcastle 2 West Ham 2.
Last five league matches: West Ham D W D D L, Newcastle L L W W L.
Top scorers: Di Canio (West Ham) 5; Lua-Lua (Newcastle) 5.
Match odds: H 13/10 A 13/8 D 9/4.
Referee: M Riley (Leeds).
Sunday
Bradford (19th) v Leeds United (9th)
Braford's Stan Collymore, signed on a free from Leicester, is apparently not match fit. Manager Chris Hutchings is without defenders Andy O'Brien (collarbone), Andy Myers (hamstring) and former Leeds duo David Hopkin (ankle) and Gunnar Halle (foot). Leeds manager David O'Leary is likely to field the same line-up which kicked off the Champions League draw with Barcelona.
Last season: Bradford 1 Leeds 2, Leeds 2 Bradford 1.
Last five league matches: Bradford L L D L L, Leeds L D W W L.
Top scorers: Carbone, Windass (Bradford) 3; Smith (Leeds) 9.
Match odds: H 5/2 A 10/11 D 11/5.
Referee: G Barber (Tring).
Liverpool (3rd) v Everton (14th) - Jamie Carragher (calf) is Liverpool's major injury worry but Steven Gerrard is back in contention. Manager Gerard Houllier will not risk Michael Owen, but will have Sami Hyypia back. Everton manager Walter Smith is likely to keep the same side that won at Newcastle last week.
Last season: Everton 0 Liverpool 0, Liverpool 0 Everton 1.
Last five league matches: Liverpool D D L W W, Everton L D L D W
Top scorers: Owen (Liverpool) 8; Jeffers (Everton) 7.
Match odds: H 8/11 A 7/2 D 21/10.
Referee: P Durkin (Dorset).
