Magners League: Shane Horgan will start on the right wing in a Leinster backline which features fellow Ireland internationals Girvan Dempsey and Gordon D'Arcy, who partners Fergus McFadden at centre for tomorrow's Magners League encounter at Murrayfield.
In the pack, Sean O'Brien forms a backrow partnership with Cameron Jowitt and Stephen Keogh. Ireland duo Trevor Hogan and captain Leo Cullen start in the secondrow for Leinster's second away trip in five days.
"There's a lot of confidence in the squad right now,” said O’Brien. “The Harlequins win has given us a lift and we know that the real hard work starts now. There are a few places up for grabs so the message for those of us who weren't involved last week is that we will have to work hard to get into the team.
"The work ethic in the team has been strong all season and over the last few months we have fight hard to win tight games. Personally, this year has gone well.
Of his own situation O’Brien is happy to be involved at this level. "I have enjoyed getting a run of games and being involved in big games, like the Wasps victory at home, gave me a taste of the level that's required. It's up to us this weekend to make a mark and take our chances.
"We have come up against tough teams throughout the league and Edinburgh will be formidable opponents on Friday. (Mike) Blair is a big threat and he really gets their backline moving. Their pack is very strong and we will have to match them up front if we are to get anything from the game.
"We've got to go over to Edinburgh and be positive and strong-minded. If we believe in ourselves and perform to the best of our ability, then we will be in contention and it is vital that we front up from the off."
Elsewhere Connacht announced a 26-man squad ahead of their match against leaders Munster at Thomond Park on Saturday (kick off: 7.30pm).
In the backs, Daniel Riordan, Aidan Wynne and Mel Deane have all been called up to the squad, while up front David Nolan and David Gannon are added as Connacht prepare to head for Limerick on Saturday.
The starting XV will be finalised at midday tomorrow.
Leinster (v Edinburgh):G Dempsey, S Horgan, F McFadden, G D'Arcy, S Keogh, I Nacewa, C Keane, R McCormack, J Fogarty, S Knoop, L Cullen (C), T Hogan, C Jowitt, S O'Brien, S Keogh. Replacements: B Blaney, O le Roux, D Toner, K McLaughlin, P O'Donohoe, I McKinley, G Brown
Connacht squad: L Bibo, A Browne, F Carr, S Cronin, M Deane, G Duffy, A Dunne, A Farley, A Flavin, D Gannon, I Keatley, R Loughney, B McGovern, J Muldoon, F Murphy, T Nathan, D Nolan, J O'Connor, R Ofisa, C O'Loughlin, C Rigney, D Riordan, M Swift, N Ta'auso, B Wilkinson, A Wynne.