England 42 Scotland 20: Jonny Wilkinson delivered a record-breaking performance on his Twickenham comeback as England launched Brian Ashton's coaching era by regaining the Calcutta Cup.
The inspirational outhalf amassed 27 points from a try, drop-goal, five penalties and two conversions to leave Scotland wishing he had stayed away.
Wilkinson had missed England's last 30 Test matches through a combination of injury and illness, but he found his feet again with ease after just 45 minutes' rugby in 12 weeks as his team made a flying start to the Six Nations.
He broke his Newcastle mentor Rob Andrew's Calcutta Cup individual record of 24 points set in 1995, but, far more importantly, he gave England renewed confidence, composure and authority after Scotland's forwards enjoyed early supremacy.
While Wilkinson, a bloodied hero following an early collision, took top billing, wing Jason Robinson and scrum-half Harry Ellis ran him close.
Robinson, making his first England appearance since retiring from Test rugby in 2005, scored two tries, while Ellis proved a constant threat to the Scottish defence with his pace and eye for the gap.
Robinson's Sale Sharks colleague Magnus Lund added a late try to confirm England's margin of superiority, and although former Great Britain rugby league skipper Andy Farrell had his moments, it was a day when Wilkinson put England back on track.
The world champions proved a shambles under Andy Robinson throughout 2006, yet their 2007 Six Nations campaign is off to a promising start.
Scotland claimed tries from Simon Taylor and Rob Dewey, while Chris Paterson kicked the remainder of their points, and while they hardly deserved a 22-point losing margin, Wilkinson's class told a devastating story.