Premiership fixtures: Chelsea begin their league title defence with a home game against Manchester City on August 19th, while Manchester United host Fulham.
The big-spending Stamford Bridge club, who did the double over Stuart Pearce's men last season, then face away matches at Middlesbrough and Blackburn.
Last season's runners-up United open up at home to Fulham before going south to face Charlton and new-boys Watford in August.
But United have a tough start to September with Old Trafford clashes against Arsenal and Tottenham on September 9th and 16th.
Alex Ferguson's side will have to wait until December 9th for their first derby clash of the season, at home to arch-rivals City.
Beaten Champions League finalists Arsenal begin life at the Emirates Stadium with a first-day game against Aston Villa before hitting the road north to Wigan and Manchester City.
Liverpool will also fancy their chances of mounting a serious title challenge and their credentials face an early test at newly-promoted Sheffield United.
Newcastle and West Ham then visit Anfield, with the first Merseyside derby of the season taking place at Goodison Park on September 9th.
Spurs - who start at Bolton - travel to Arsenal on December 2nd and must wait until November 4th to meet Chelsea at home.
Championship winners Reading meet Gareth Southgate's Middlesbrough at the Madejski Stadium in their first top flight game, then travel to Aston Villa on August 23rd and Wigan just three days later.
Royals boss Steve Coppell will welcome his former club Manchester United on September 23rd and Chelsea on October 14th.
Sheffield United travel to White Hart Lane after their opener with Liverpool, while Watford's Premiership return begins with a trip to Everton, followed by home matches against West Ham and Manchester United.
Newcastle open the season at home to Wigan, albeit without knee injury victim Michael Owen.
The Magpies then have away games at Liverpool and Aston Villa - the first North-East derby of the season takes place at Middlesbrough on October 21th.
Portsmouth, who pulled off a great escape to avoid relegation last season, start 2006-07 with a home game against Blackburn at Fratton Park, while the other top-flight opener sees West Ham and Charlton meet in a London derby at Upton Park.
Opening fixtures
August 19th
Arsenal v Aston Villa
Bolton v Tottenham
Chelsea v Man City
Everton v Watford
Man Utd v Fulham
Newcastle v Wigan
Portsmouth v Blackburn
Reading v Middlesbrough
Sheff Utd v Liverpool
West Ham v Charlton
August 22nd
Charlton v Man Utd
Middlesbrough v Chelsea
Tottenham v Sheff Utd
Watford v West Ham
Wigan v Arsenal
August 23rd
Aston Villa v Reading
Blackburn v Everton
Fulham v Bolton
Liverpool v Newcastle
Man City v Portsmouth
