Reading will continue their policy of using squad players in the FA Cup when they travel to Manchester United for Saturday's fifth-round tie.
Boss Steve Coppell made a raft of changes for the cup victories over Burnley and Birmingham as he honoured his pledge to prioritise the Barclays Premiership.
First team coach Kevin Dillon revealed Coppell will continue tinkering with his starting line-up once again despite the daunting trip to Old Trafford.
"Steve is very consistent in his selections so I'm sure there will be changes to the team that played against Villa," Dillon told the club's website, readingfc.co.uk.
"But it will be quality players who come in. We'll be changing the team - but not necessarily weakening it.
"If you look at the squad now it's very strong. Whoever plays, the team on Saturday will have plenty of international players.
"We'll have people on the bench who can come on and change the game if needed."
Reading are currently eyeing European football next season as they occupy sixth in the Premiership.