Saturday (3pm unless stated)
West Ham (4) v Chelsea (1), 12.30pm – Live BT Sport 1
West Ham are likely to still be without Aaron Cresswell due to a back problem, although he has returned to doing some light training. Angelo Ogbonna remains sidelined with a cruciate ligament injury.
Reece James and Jorginho have handed injury-hit Chelsea a double fitness boost after recovering from their recent knocks. The Blues still do not know the extent of Trevoh Chalobah’s hamstring problem but the defender will definitely miss Saturday’s match, while Mateo Kovacic (hamstring), N’Golo Kante (knock) and Ben Chilwell (knee) will also be absent.
Last season: West Ham 0 Chelsea 1, Chelsea 3 West Ham 0
Last five league matches: West Ham W W L L D; Chelsea W D W D W
Top scorers (all competitions): Michail Antonio (West Ham) 7; Reece James (Chelsea) 5
Match odds: H: 19-5; D: 27-10; A: 3-4
Referee: Andre Marriner
Newcastle (20) v Burnley (18) – Live Premier Sports 2
Newcastle will be without the suspended Ciaran Clark but fellow central defender Jamaal Lascelles and wing back Matt Ritchie are available after serving one-match bans. Manager Eddie Howe will otherwise assess a series of bumps and bruises, but defender Paul Dummett (calf) is his only remaining absentee.
Burnley welcome back defender James Tarkowski and midfielder Ashley Westwood from suspension. Forward Ashley Barnes remains out due to a thigh injury and defender Phil Bardsley, who missed the draw at Wolves with an unspecified problem, is doubtful. Midfielder Dale Stephens, who has had Covid-19, is also set to miss out.
Last season: Burnley 1 Newcastle 2, Newcastle 3 Burnley 1
Last five league matches: Newcastle L D D L D; Burnley D W D D D
Top scorers (all competitions): Callum Wilson (Newcastle) 5; Chris Wood and Maxwel Cornet (Burnley) 5
Match odds: H: 13-10; D: 23-10; A: 9-4
Referee: Paul Tierney
Southampton (16) v Brighton (9)
Jan Bednarek is absent after suffering a calf injury against Leicester. Stuart Armstrong is out with a heel complaint, while goalkeeper Fraser Forster picked up a knock in training and will also be out of action. Defender Jack Stephens is building fitness after a long-term knee injury.
Brighton will be without Jeremy Sarmiento (hamstring), Adam Webster (calf) and former Southampton midfielder Adam Lallana (leg) after all three were injured against West Ham.
Last season: Southampton 1 Brighton 2, Brighton 1 Southampton 2
Last five league matches: Southampton W W L L D; Brighton D D L D D
Top scorers (all competitions): Che Adams, Armando Broja and Mohamed Elyounoussi (Southampton) 4; Neal Maupay and Kaoru Mitoma (Brighton) 5
Match odds: H: 29-20; D: 11-5; A: 2-1
Referee: Anthony Taylor
Wolves (8) v Liverpool (3)
Wolves have Ruben Neves available after suspension. Daniel Podence may return after self-isolating having tested positive for Covid-19 but Marcal (Covid) is out. Jonny and Pedro Neto (both knee) are also sidelined along with Yerson Mosquera (hamstring) and Willy Boly (muscle).
Liverpool defender Joe Gomez and midfielder Naby Keita have returned to training after almost six weeks out but will not be ready for the weekend. The pair, sidelined by calf and hamstring injuries respectively, are likely to be back in the squad for Tuesday’s Champions League group match against AC Milan.
Last season: Wolves 0 Liverpool 1, Liverpool 4 Wolves 0
Last five league matches: Wolves W L W D D; Liverpool D L W W W
Top scorers (all competitions): Hwang Hee-chan (Wolves) 4; Mohamed Salah (Liverpool) 19
Match odds: H: 7-1; D: 18-5; A: 2-5
Referee: Chris Kavanagh
Watford (17) v Manchester City (2), 5.30pm – Live Sky Sports
Adam Masina was forced off in the first half against Chelsea and joins a Hornets injury list which already includes Ismaila Sarr, Ben Foster and Nicolas Nkoulou, who are all sidelined until January. Francisco Sierralta (hamstring), Peter Etebo (quad) and Kwadwo Baah (ankle) are also out.
City playmaker Kevin De Bruyne is back in training after recovering from coronavirus while Ilkay Gündogan, John Stones and Kyle Walker – all missing at Aston Villa – are also available again. Aymeric Laporte returns from suspension and, with Phil Foden and Jack Grealish on the bench on Wednesday after recent knocks, only Ferran Torres (foot) remains on the injury list.
Last season: No corresponding fixture
Last five league matches: Watford L L W L L; Man City L W W W W
Top scorers (all competitions): Emmanuel Dennis (Watford) 6; Riyad Mahrez (Man City) 8
Match odds: H: 14-1; D: 11-2; A: 1-5
Referee: Kevin Friend
Sunday (2pm unless stated
Leeds United (15) v Brentford (12)
Leeds duo Patrick Bamford (ankle) and Luke Ayling (knee) are expected to be available after lengthy injury absences, with both having come through a run-out for the under-23s on Monday. Pascal Struijk suffered a minor hip injury in the win over Crystal Palace but is expected to be fit.
Brentford boss Thomas Frank has no new injury problems for the trip to Elland Road. Kristoffer Ajer has several more weeks in the treatment room as he recovers from a hamstring injury and Tariqe Fosu (also hamstring) continues to be assessed, while Mathias Jorgensen is still sidelined.
Last season: No corresponding fixture
Last five league matches: Leeds W D L D W; Brentford L L D W L
Top scorers (all competitions): Raphael Raphinha (Leeds) 6; Yoane Wissa, Ivan Toney and Marcus Forss (Brentford) 5
Match odds: H: 1-1; D: 5-2; A: 29-10
Referee: David Coote
Manchester United (7) v Crystal Palace (11)
Ralf Rangnick has some injury issues to check on ahead of his first match as interim Manchester United manager. Paul Pogba (hamstring) and Raphael Varane (thigh) remain absent but Aaron Wan-Bissaka could return after a hand injury ruled him out against Arsenal. Edinson Cavani and Luke Shaw could miss out. Nemanja Matic (hamstring) is out and Cristiano Ronaldo is doubtful after he was substituted late on Thursday.
Palace right back Joel Ward is suspended after receiving his fifth booking of the season. Eagles boss Patrick Vieira is also without James McArthur (hamstring) while Nathan Ferguson continues to build up his fitness having not made a first-team appearance since January due to numerous injury issues. Joachim Andersen (hamstring) will be assessed after missing the last two matches.
Last season: Crystal Palace 0 Man Utd 0, Man Utd 1 Crystal Palace 3
Last five league matches: Man Utd W L L D W; Crystal Palace W W D L L
Top scorers (all competitions): Cristiano Ronaldo (Man Utd) 12; Odsonne Edouard (Crystal Palace) 6
Match odds: H: 11-20; D: 16-5; A: 5-1
Referee: Craig Pawson
Tottenham (6) v Norwich (19)
Tottenham have no fresh injury concerns with Cristian Romero (hamstring) and Giovani Lo Celso (knee) the only absentees. Romero is out until 2022 while Lo Celso will return to training next week.
Norwich forward Milot Rashica has been ruled out for up to a month with a groin injury. Mathias Normann (pelvis) is out along with Christoph Zimmermann (ankle) and long-term absentee Sam Byram but Todd Cantwell is available after having to self-isolate.
Last season: No corresponding fixture
Last five league matches: Tottenham L L D W W; Norwich L W W D D
Top scorers (all competitions): Harry Kane and Son Heung-min (Tottenham) 6; Teemu Pukki (Norwich) 5
Match odds: H: 2-5; D: 18-5; A: 15-2
Referee: Jarred Gillett
Aston Villa (13) v Leicester (10), 4.30pm – Live Sky Sports
Villa are set to be without Leon Bailey for "a number of weeks" after he hobbled off with what looked like a thigh problem during Wednesday's 2-1 home defeat to Manchester City. An unspecified injury has kept Danny Ings out recently but the striker is nearing a return and a decision will be made on his fitness on Saturday.
Youri Tielemans and James Justin have both resumed training but Sunday’s match may come too soon. James Maddison is being treated for a glute issue following the draw at Southampton but the midfielder is expected to be fit. Ricardo Pereira (hamstring) and long-term absentee Wesley Fofana remain out.
Last season: Aston Villa 1 Leicester 2, Leicester 0 Aston Villa 1
Last five league matches: Aston Villa L L W W L; Leicester L D L W D
Top scorers (all competitions): Cameron Archer and Ollie Watkins (Aston Villa) 4; Jamie Vardy (Leicester) 9
Match odds: H: 11-8; D: 12-5; A: 2-1
Referee: Michael Oliver
