Arsenal (4) v Manchester United (3)Arsenal forward Robin van Persie is suspended while Emmanuel Adebayor (ankle) and Emmanuel Eboue (knee) will also miss out, along with long-term absentees Tomas Rosicky and Eduardo.
Late checks will be made on Mikael Silvestre (nose), William Gallas (hamstring), Bacary Sagna (ankle) and Theo Walcott (shoulder).
Wes Brown (ankle) and long-term absentees Paul Scholes and Owen Hargreaves are sidelined for United. Darren Fletcher (knee) is a doubt but captain Gary Neville is fit.
Last season:Man Utd 2 Arsenal 1, Arsenal 2 Man Utd 2.
Last five league matches:Arsenal D W W D L; Man Utd W W D W W
Top scorers:Emmanuel Adebayor (Arsenal) 9; Cristiano Ronaldo (Man Utd) 7
Match odds:H 7-4 A 13-10 D 21-10
Referee:Howard Webb (S Yorkshire).
Hull (6) v Bolton (18)
Captain Ian Ashbee should return from suspension, having been forced to sit out the 4-3 defeat at Manchester United last weekend after picking up five bookings.
Record signing Anthony Gardner will not play due to a thigh injury, while Bernard Mendy — who scored and won a penalty against United — and midfielder Stelios Giannakopoulos are being considered for starts against their former club.
Striker Johan Elmander is set to return for Bolton after recovering from a groin strain. Midfielder Riga also comes into contention after an ankle problem but captain Kevin Nolan is suspended.
Last season:No corresponding fixture
Last five league matches:Hull W W W L L; Bolton W D L L W
Top scorers:Geovanni (Hull) 5; Kevin Davies (Bolton) 4
Match odds:H 21-20 A 21-10 D 11-5
Referee:Alan Wiley (Staffordshire).
Liverpool (2) v West Brom (19)
Fernando Torres is back in Liverpool's squad after missing six games with a hamstring injury. The Spanish striker is expected to start the match against the Baggies although Reds boss Rafael Benitez will not make a firm decision until nearer kick-off.
West Brom are once again without central defenders Leon Barnett (knee) and Abdoulaye Meite (calf), but Scotland midfielder James Morrison is fit to play after recovering from the back problem that forced him off against Blackburn last Saturday.
Midfielder Filipe Teixeira, who has not played since March due to a knee ligament injury, is set to return to the squad.
Last season:No corresponding fixture
Last five league matches:Liverpool W W W W L; West Brom W L L L D
Top scorers:Dirk Kuyt & Steven Gerrard (Liverpool) 6; Roman Bednar (West Brom) 4
Match odds:H 1-5 A 10-1 D 4-1
Referee:Peter Walton (Northamptonshire).
Sunderland (15) v Portsmouth (9)
Sunderland defender George McCartney is a doubt. The full back suffered a foot injury in last weekend's 5-0 defeat at Chelsea, although manager Roy Keane is hopeful he will make the game at the Stadium of Light.
Goalkeeper Craig Gordon is still struggling with an ankle problem, so Marton Fulop is likely to continue, while striker Michael Chopra has returned to Cardiff on loan.
Niko Kranjcar is in line to make his first start for Portsmouth since the opening day of the season after recovering from ankle ligament damage.
David Nugent, another long-term absentee, is also available again after recovering from a groin injury which required surgery.
Last season:Portsmouth 1 Sunderland 0, Sunderland 2 Portsmouth 0
Last five league matches:Sunderland D D W L L; Portsmouth W D D L L
Top scorers:Djibril Cisse (Sunderland) 3; Peter Crouch & Jermain Defoe (Portsmouth) 6
Match odds:H 5-4 A 7-4 D 11-5
Referee:Steve Bennett (Kent).
West Ham (11) v Everton (7)
Scott Parker has recovered from his calf injury and will be fit to start. Midfielders Mark Noble (calf) and Valon Behrami (groin) remain unavailable, and striker Carlton Cole completes a three-match ban.
Striker Diego Tristan will be on the bench should he recover from a leg injury, with the fitness of defender Calum Davenport (thigh) also being monitored.
Everton have injury doubts over Ayegbeni Yakubu (heel) and Steven Pienaar (knee), while Marouane Fellaini is serving a one match suspension after picking up a fifth booking of the season.
Moyes could hand a starting berth to defensive midfielder Segundo Castillo after he came through a reserve game unscathed this week.
Last season:Everton 1 West Ham 1, West Ham 0 Everton 2
Last five league matches:West Ham L L L L D; Everton D L D W W
Top scorers:Carlton Cole (West Ham) 4; Ayegbeni Yakubu (Everton) 4
Match odds:H 7-5 A 8-5 D 21-10
Referee:Mark Halsey (Lancashire).
Wigan (17) v Stoke (12)
Wigan skipper Mario Melchiot has shown no after-effects from a recent virus and should be available. Steve Bruce may elect to replace Jason Koumas with either Paul Scharner or Michael Brown alongside Lee Cattermole in midfield to add a more physical presence.
Stoke manager Tony Pulis is expected to name an unchanged side after his team beat Arsenal last weekend. Amdy Faye was preferred to Tom Soares for last week's shock win over the Gunners and the Senegal international is set to retain his place.
Last season:No corresponding fixture
Last five league matches:Wigan L L L L W; Stoke L W L W W
Top scorers:Amr Zaki (Wigan) 9; Ricardo Fuller (Stoke) 5
Match odds:H 8-11 A 10-3 D 11-5
Referee:Mike Riley (Yorkshire).
Sunday
Aston Villa (5) v Middlesbrough (8)
Villa have been boosted by the return to fitness of winger James Milner after he missed Thursday night's Uefa Cup tie against Slavia Prague. Midfielder Stiliyan Petrov will miss a third successive game as he is still being troubled by a hamstring strain.
Afonso Alves and top scorer Mido are vying to partner Tuncay Sanli in attack for Boro. Justin Hoyte is expected to be named at right back against Villa, relegating David Wheater to the bench, while Julio Arca is poised to replace Didier Digard in central midfield.
Last season:Aston Villa 1 Middlesbrough 1, Middlesbrough 0 Aston Villa 3
Last five league matches:Aston Villa L D W W L; Middlesbrough W L D W D
Top scorers:Gabriel Agbonlahor (Aston Villa) 7; Mido (Middlesbrough) 5
Match odds:H 8-13 A 4-1 D 23-10
Referee:Rob Styles (Hampshire).
Blackburn (13) v Chelsea (1)
Blackburn are likely to be without leading strikers Benni McCarthy and Roque Santa Cruz. McCarthy is suspended while Santa Cruz is a major doubt with a calf tear.
Brett Emerton (hamstring) is also out while his fellow Australian Vince Grella is another doubt, also with a hamstring injury.
Chelsea left back Ashley Cole will miss the match with a calf problem. Wayne Bridge will continue to deputise but defender Ricardo Carvalho (hamstring) and Michael Ballack (foot) and Michael Essien (knee) remain out. Brazilian defensive midfielder Mineiro could make his first start for the Blues.
Last season:Blackburn 0 Chelsea 1, Chelsea 0 Blackburn 0
Last five league matches:Blackburn L D D L D; Chelsea W W L W W
Top scorers:Matt Derbyshire (Blackburn) 3; Nicolas Anelka (Chelsea) 9
Match odds:H 11-2 A 4-9 D 13-5
Referee:Chris Foy (Merseyside).
Fulham (16) v Newcastle (14)
Fulham forward Seol Ki-Hyeon remains doubtful to play a part at Craven Cottage. He has returned from his trip to South Korea, granted for personal reasons, but is still struggling with a knee injury.
Defender Toni Kallio has shaken off his virus but Fredrik Stoor is unavailable because of a cold and Dickson Etuhu will not be back in training until Monday.
Newcastle captain Michael Owen returned from a groin injury as a late substitute in the 2-0 victory over Aston Villa on Monday night, but interim boss Joe Kinnear is likely to stick with the 11 men who secured a second successive league win.
Midfielder Danny Guthrie may join Owen among the substitutes after missing out because of Nicky Butt's return against Villa.
Last season:Newcastle 2 Fulham 0, Fulham 0 Newcastle 1
Last five league matches:Fulham L D D W L; Newcastle D D L W W
Top scorers:Zoltan Gera, Andrew Johnson & Danny Murphy (Fulham) 2; Michael Owen (Newcastle) 5
Match odds:H 6-5 A 15-8 D 21-10
Referee:Martin Atkinson (W Yorkshire).
Manchester City (10) v Tottenham (20)
Manchester City midfielder Vincent Kompany is suspended after picking up five bookings. Benjani Mwaruwari is pushing for a place in the starting line-up after marking his return from a thigh injury with a goal.
Vedran Corluka and Roman Pavlyuchenko come back into the squad after being cup-tied in the Uefa Cup. Jamie O'Hara was suspended for the win over Dinamo Zagreb and returns, while Ledley King is in contention after being rested. Giovani dos Santos (ankle) is out and Jermaine Jenas (toe) has been struggling.
Last season:Man City 2 Tottenham 1, Tottenham 2 Man City 1
Last five league matches:Man City L D W L L; Tottenham L L W D W
Top scorers:De Souza Robinho (Man City) 6; Darren Bent (Tottenham) 6
Match odds:H 23-20 A 19-10 D 11-5
Referee:Mike Dean (Wirral).
