Blackburn (15) v Middlesbrough (16)Brad Friedel will continue in goal for Blackburn despite being troubled by a dead leg. He was unable to take goal-kicks during the St Stephen's Day win over Liverpool.

Middlesbrough welcome back James Morrison (calf) and Abel Xavier (hamstring) to the squad after they missed the St Stephen's Day draw with Everton. Julio Arca is struggling to prove his fitness after picking up a hip injury in training, while Robert Huth (foot) will be out until the middle of January at the earliest.

Bolton (4) v Portsmouth (5)

Bolton midfielder Ivan Campo is available in spite of picking up his fifth booking of the season in the St Stephen's Day win over Newcastle. The seven-day rule allows him to face both Pompey and Liverpool on New Year's Day.

Portsmouth manager Harry Redknapp has no fresh injury worries and looks set to make just one change to the team which won at West Ham on St Stephen's Day. He will opt for Zimbabwean striker Benjani Mwaruwari instead of top scorer Kanu.

Charlton (19) v Aston Villa (10)

Charlton winger Jerome Thomas has been feeling the effects of a recent virus and may not feature against Aston Villa. Midfielder Amdy Faye is struggling to shake off an undisclosed injury, while Darren Ambrose will expect to retain his place following a goal on Wednesday night and Dennis Rommedahl is pressing for a start. Andy Reid (hamstring) and captain Luke Young (knee) are both definitely out.

Chris Sutton will be sidelined for at least six weeks with blurred vision and concussion, while Villa manager Martin O'Neill is hoping defenders Olof Mellberg and Aaron Hughes will have shaken off knee injuries picked up against Tottenham on St Stephen's Day. But midfielder Stiliyan Petrov is a major doubt after aggravating his hamstring injury at White Hart Lane.

Chelsea (2) v Fulham (12)

Chelsea coach Jose Mourinho has more defensive worries with Khalid Boulahrouz out through suspension. Captain John Terry (back) and Joe Cole (foot) were already out of contention.

Dutch striker Collins John has been called up by Fulham to replace the suspended Heider Helguson. Fulham are also without midfielder Claus Jensen (groin). Captain Luis Boa Morte returns from injury to replace Jensen on the bench even though he is not yet considered fit enough for a full 90 minutes.

Everton (8) v Newcastle (11)

Everton manager David Moyes welcomes defender Phil Neville back from suspension and does not expect any new injuries to contend with, although Alan Stubbs will face a late test on the knee problem which forced him out of the St Stephen's Day draw with Middlesbrough.

Newcastle boss Glenn Roeder will make late checks on goalkeeper Shay Given and stand-in full-back Nolberto Solano. Both men are battling against the groin injuries which kept them out of Tuesday's 2-1 defeat at Bolton, and Pavel Srnicek and David Edgar are standing by.

Man Utd (1) v Reading (9)

Michael Carrick returns to the Manchester United squad for tomorrow's clash with Reading at Old Trafford after an ankle injury. Paul Scholes and Nemanja Vidic are suspended, so Rio Ferdinand is set to return along with Ryan Giggs, Gary Neville and Louis Saha, who all sat out the St Stephen's Day win over Wigan.

Reading have no new injury worries ahead of tomorrow's trip to Manchester United. Winger Bobby Convey is back in training following a knee operation but will not be considered for the Old Trafford clash. Striker Dave Kitson is also on the comeback trail.

Sheff Utd (17) v Arsenal (3)

Danny Webber, Claude Davis, Michael Tonge and Keith Gillespie have been struck by a virus and manager Neil Warnock will leave it as late as possible to assess the quartet's fitness. Stephen Quinn (fibula) and Derek Geary (thigh) are definitely out.

Arsenal will be without Emmanuel Adebayor after he suffered a thigh injury at Watford on St Stephen's Day. Brazilian Julio Baptista could be handed a rare start, but defender Johan Djourou (hamstring) and full-back Emmanuel Eboue (ankle) are concerns. Lauren may make a welcome return to the squad following his long-term injury lay-off, but captain Thierry Henry (sciatic nerve), William Gallas (thigh) and Freddie Ljungberg (hamstring) are still sidelined.

Tottenham (7) v Liverpool (6)

Tottenham will be without Robbie Keane (knee) and Jermaine Jenas (ankle), who are expected to return in January. Aaron Lennon (knee) and Mido (groin) missed the St Stephen's Day win over Aston Villa and remain concerns.

Dirk Kuyt is in line to return to the Liverpool starting line-up for tomorrow's trip to Tottenham after impressing from the bench in the St Stephen's Day defeat at Blackburn. Peter Crouch is the most obvious candidate to make way for Kuyt after failing to make the most of a series of fine chances at Ewood Park. Jermaine Pennant, Luis Garcia and Sami Hyypia are among those also pushing for recalls while boss Rafael Benitez does not expect any new injuries to contend with.

Watford (20) v Wigan (14)

Watford will hand a late fitness test to Danny Shittu (ankle) while Hameur Bouazza is expected to be out for up to six weeks with a dislocated shoulder and Marlon King is out until the end of the season with a knee injury. James Chambers (gash) and Clarke Carlisle (muscle) are also missing.

Wigan captain Arjan de Zeeuw returns to the side after a toe injury. But manager Paul Jewell is again without striker Henri Camara (knee), winger Lee McCulloch (suspended) and midfielder Paul Scharner (knee surgery) while Ryan Taylor, Antonio Valencia and Steve McMillan are also sidelined. Striker
Svetoslav Todorov plays his last game of a four-month loan deal from Portsmouth.

West Ham (18) v Man City (13)

Nigel Reo-Coker and Paul Konchesky are suspended for the Barclays Premiership clash against Manchester City at Upton Park. James Collins is back in training following a groin injury, while Dean Ashton continues his rehabilitation from a broken ankle suffered at the start of the season.

Manchester City boss Stuart Pearce could be forced to push Micah Richards into midfield. Dietmar Hamann (back) and Claudio Reyna (hamstring) are injured, while Joey Barton starts a three-match ban. Paul Dickov (toe) and Darius Vassell (groin) are both major doubts.