Champions League/Valencia v Inter Milan:Internazionale striker Adriano is a major injury worry for the Italian side ahead of tonight's last-16 return leg against Valencia at the Mestalla Stadium.
Adriano is struggling to recover from a muscle problem but has travelled to Spain in the hope of being passed fit for the meeting, which is finely poised after the first encounter ended 2-2 at the San Siro a fortnight ago.
The Spaniards will fancy their chances with the return of pivotal midfield duo Ruben Baraja and Vincente.
Roberto Mancini is likely to leave Adriano on the bench and play instead with Hernan Crespo alongside in-form Ibrahimovic, while Valencia will have Fernando Morientes and David Villa up front.
The Nerazzurri will be without injured midfield duo Patrick Vieira and Esteban Cambiasso.
Olympique Lyon v AS Roma
Lyon go into tonight's tie against Roma having rediscovered their form of the start of the season.
The reigning five-time French champions have won three of their last four league games and picked up a decent goalless draw in the first leg against Roma at the Stadio Olimpico.
Sylvain Wiltord, Alou Diarra and Fred have all returned from thigh problems, with the last two set to start tonight.
France anchorman Diarra, who has been sidelined for two months, should take the place of the suspended Jeremy Toulalan in the engine room.
As far as Roma are concerned, their hopes of progressing to the tournament's quarter-finals for the first time do appear to rest with Totti. The Roma captain will lead the attack with the trio of Amantino Mancini, Rodrigo Taddei and Simone Perrotta in support.
