Manchester United and Chelsea face each other for a place in the English FA Cup semi-finals.
They were drawn against each other in yesterday's quarter-final draw - a repeat of the 1994 FA Cup final which United won 4-0.
Both clubs are going for trophies on three fronts - the Premiership, Europe and the FA Cup - but for one the treble dream will end after the showdown.
Sheffield United will play Huddersfield or Derby if they beat Arsenal in the Highbury re-match following the controversial end to their fifth round clash on yesterday.
Leeds United have the incentive of an all-Yorkshire clash with Barnsley at Oakwell if they beat Tottenham in the fifth round replay at White Hart Lane on Wednesday week.
Everton have a chance to put their gloomy Premiership season behind them with an away tie at the winners the Newcastle-Blackburn replay.
Manchester United full-back Denis Irwin was delighted to receive a home draw for the quarter-final stage.
"At least we're at home but it's a tough draw," he said.
"We've played them (Chelsea) twice this year and they've been two tough matches for us. I think they had the upper hand in the two matches - I think they played better."
Quarter-Final Draw:
Newcastle or Blackburn v Everton
Barnsley v Leeds or Tottenham
Arsenal or Sheffield Utd v Huddersfield or Derby
Manchester Utd v Chelsea
Matches to be played weekend of March 6th/7th.
Replay date for the fifth round are: Wed 24th Feb (7.45): Tottenham v Leeds; Derby v Huddersfield; Blackburn v Newcastle.