Jonny Wilkinson and Andy Farrell have both been included in England's 55-strong elite squad for the coming season.
Wilkinson has not played for England since the 2003 World Cup final - but is fit again after suffering a succession of injuries.
Farrell, the former Britain rugby league captain, is yet to play a competitive game of union since his cross-code switch to Saracens from Wigan. He missed last season with toe and back injuries and there remains some debate where his best position will be.
But England head coach Andy Robinson believes both men can be key figures heading into next year's World Cup defence.
"I would like to welcome back Jonny Wilkinson. Everyone hopes that he has put his injuries behind him and is able to play regularly for Newcastle Falcons," said Robinson.
"I am also looking forward to working with Andy Farrell who was in last season's EPS squad but suffered a succession of injuries.
"I am very excited about this new Elite Player Squad which faces a challenging year ahead leading into the 2007 Rugby World Cup.
"These players will form the nucleus of selection for the Investec Challenge series in the autumn and the RBS Six Nations and they should be congratulated on being included. However, as is always the case, exclusion from these squads does not mean that the selection door to England is closed."
Bath prop Matt Stevens was not considered after further shoulder surgery.
The leading omission is Wasps winger Tom Voyce, while there is no place for Leicester prop Graham Rowntree or Gloucester lock Alex Brown.
The squad is made up of 40 senior England players and a 15-man national academy squad.